<?xml version="1.0" encoding="utf-8"?>
<Journal>
<Journal-Info>
<name>International Journal of Pharma and Bio Sciences</name>
<website>ijpbs.net</website>
<email>editorijpbs@rediffmail.com (or) editorofijpbs@yahoo.com (or) prasmol@rediffmail.com</email>
</Journal-Info>
<article>
<article-id pub-id-type='other'>10.22376/ijpbs.2019.10.1.p1-12</article-id>
<issue_number>Volume 5 Issue 4</issue_number>
<issue_period>2014 (October - December)</issue_period>
<title>SYNTHESIS OF P38 MAP KINASE INHIBITOR ANALOGUES COMPOUNDS AND QUINOXALINONE DERIVATIVES </title>
<abstract>This paper reports the synthesis of nitrogen containing heterocyclic compounds such as quinoxalines (5-7), imidazoles (8, 9,10,11), aminothiazole (12), aminooxazole (13), aminoimidazole (14) and benzothiazine (17) from the reaction with unsymmetrical diketone 4, 3 and 4a respectively. The aforementioned compounds with 4-pyridyl,4-fluorophenyl groups have different positions in their ring skeleton. The quinoxalinone derivatives (19, 20) were synthesized by the reaction of (18) with o-phenylenediamine and 4,5-dimethyl- o-phenylenediamine respectively.</abstract>
<authors>KUO CHU HWANG  AND  PERIYASAMY MURUGAN</authors>
<keywords>p38 MAP kinase inhibitor, inflammatory, triarylimidazole, unsymmetrical diketones, benzothiazine, 1,3,5- trione, o-phenylenediamine, quinoxalinone.</keywords>
<pages>212-224</pages>
</article>
</Journal>
