10.22376/ijpbs.2019.10.1.p1-12 Volume 5 Issue 4 2014 (October - December) 1 lessThan b greaterThan ' lessThan /b greaterThan -Acetoxychavicol acetate (ACA) is a phenylpropanoid present in lessThan i greaterThan Alpinia galanga lessThan /i greaterThan (L) Willd syn. lessThan i greaterThan Languas galanga lessThan /i greaterThan . The objective of this study was to isolate 1 lessThan b greaterThan ' lessThan /b greaterThan -Acetoxychavicol acetate (ACA) from acetone extract of lessThan i greaterThan Alpinia galanga lessThan /i greaterThan (AEAG) and evaluate anti-arthritic activity of 1 lessThan b greaterThan ' lessThan /b greaterThan -Acetoxychavicol acetate (ACA) and acetone extract of lessThan i greaterThan Alpinia galanga lessThan /i greaterThan (AEAG) on complete Freund's Adjuvant-induced arthritis in rats. Radiographic and histopathological observations were evaluated. AEAG (400 mg/kg) and ACA (10 and 20 mg/kg) suppressed the paw swelling, increased the paw withdrawal latency, and reduced the paw thickness in arthritic rats. Radiological and histopathological characteristics in ACA (20 mg/kg) treated rats were comparable with that of diclofenac treated rats. The present study indicates that ACA and AEAG showed significant antiarthritic activity. VIJAYKUMAR M. KALE AND AJAY G.NAMDEO 1'-Acetoxychavicol acetate, Anti-arthritic, Acetone extract of Alpinia galanga, Complete Freund’s adjuvant. 09-19