10.22376/ijpbs.2019.10.1.p1-12 Volume 5 Issue 3 2014 (July- September) Pre-eclampsia (PE) is a unique syndrome in human pregnancy. To assess the effect of coalesce strategies on PE, a randomized clinical trial on 240 at risk primigravid mothers, by proportionate stratified random sampling was conducted. Mothers were stratified as Group A-age lessThan 18 years, Group –B age greaterThan 30 years & Group C mothers BMI ≥30kgm lessThan sup greaterThan 2 lessThan /sup greaterThan -obese).Coalecse strategies (Increased dose of calcium lactate supplementation from 300 mg to 1500 and stretching exercises) were given to the study group from 17 weeks of gestation till the end of pregnancy. Subjects were assessed for SBP, DBP, and proteinuria at scheduled visits in both the groups.Maternal, fetal and neonatal outcome were assessed at the end of the delivery lessThan b greaterThan . lessThan /b greaterThan Results showed that 17 out of 108 mothers in the study and 31 out of 103 mothers in control group developed PE at the end of pregnancy at lessThan i greaterThan p≤ lessThan /i greaterThan 0.001 level ( lessThan i greaterThan t lessThan /i greaterThan =4582.50, lessThan i greaterThan p= lessThan /i greaterThan 0.003**). Study concludes that coalesce strategies were found effective in the prevention of PE and confers a favorable maternal, fetal, and neonatal outcome. PROF. K.LATHA*1 AND DR.PROF.A.JUDIE 2 Coalesce strategies,pre-eclampsia,pregnancy,calcium supplementation,stretching exercises 1074-1086