10.22376/ijpbs.2019.10.1.p1-12 Volume 5 Issue 3 2014 (July- September) lessThan i greaterThan Andrographis paniculata lessThan /i greaterThan (Acanthaceae) is a potent medicinal plant in the Indian systems of medicine. Traditionally the leaves are used to treat influenza, bronchitis, gonorrohea, cholera, fertility and anti-bacterial, anti-cancer, anti-diabetic, anti-inflammatory and anti-snake venom etc. The present study describes the phytochemical profile and antimicrobial activity of lessThan i greaterThan Andrographis paniculata lessThan /i greaterThan . For the present investigation, samples of lessThan i greaterThan A. paniculata lessThan /i greaterThan extracts, obtained by extraction in ethanol,were used for their antimicrobial activity. The antimicrobial activities were assessed by measuring the diameter of the inhibition zones and MIC. This is the first report on analysis of antimicrobial components from lessThan i greaterThan A. paniculata lessThan /i greaterThan , and our results confer the utility of this plant extract in developing a novel broad spectrum antimicrobial agent. Antimicrobial activity of extract of lessThan i greaterThan Andrographis paniculata lessThan /i greaterThan was studied using ethanol against bacterial strains like Staphylococcus lessThan i greaterThan aureus lessThan /i greaterThan lessThan i greaterThan , Klebsiella pneumonia, Proteus sp., Pseudomonas aeruginosa. E.coli and lessThan /i greaterThan strains of fungi which are lessThan i greaterThan Aspergillus fumigatus lessThan /i greaterThan , lessThan i greaterThan Aspergillus flavus lessThan /i greaterThan , lessThan i greaterThan Mucorindicus, Rhizopus sp., Trichophyton mentagrophytes, Trichophyton rubrum, Candida albicans. lessThan /i greaterThan The antimicrobial activity was determined by well diffusion method and MIC for fungal strains. S. JANSIRANI AND K.G PURUSHOTHAM ANDROGRAPHIS PANICULATA, ANTIMICROBIAL ACTIVITY, WELL DIFFUSION METHOD, MINIMUM INHIBITORY CONCENTRATION (MIC) 509-514