10.22376/ijpbs.2019.10.1.p1-12 Volume 5 Issue 3 2014 (July- September) To evaluate the effect of adding midazolam to bupivacaine to prolong the analgesia characteristics of brachial plexus block. After pre- anaesthetic assessment all the patients were premedicated with diazepam 0.1mg/kg orally one hour before the surgery. Patients were randomly divided into group1 & 2. Group -1 patients received supraclavicular brachial plexus block with 30ml of 0.5% bupivacaine & group -2 patients received a mixture of 30ml of 0.5% bupivacaine & midazolam 50µg/kg body weight. On arrival in the operating room, standard base line vital signs readings were recorded. Intra –operatively HR, BP, oxygen saturation & sedation, time of establishment of sensory & motor block were recorded in all patients. Post-operatively HR, BP, sensory & motor block, pain score & sedation score, time of requirement of rescue analgesia were assessed at 0,30min,2hr,6hrs,12 hrs & 24 hrs in all patients. Demographic variables were comparable. There was no significant difference in monitoring of intra-operative & post-operative Vital signs (HR, SBP, DBP, MAP & oxygen saturation). Post–operative sedation score, pain score, requirement of rescue analgesia, sensory & motor block were significantly less in group-2 (p –value- lessThan 0.05). Conclusion-addition of midazolam to bupivacaine in brachial plexus block produces early onset of sensory and motor block, increased sedation score intraoperatively & prolongs postoperative analgesia. DR SULOCHANA DASH BRACHIALPLEXUS, SENSORY BLOCK, MOTOR BLOCK, SEDATION SCORE, PAIN SCORE, RESCUE ANALGESIA 491-498