<?xml version="1.0" encoding="utf-8"?>
<Journal>
<Journal-Info>
<name>International Journal of Pharma and Bio Sciences</name>
<website>ijpbs.net</website>
<email>editorijpbs@rediffmail.com (or) editorofijpbs@yahoo.com (or) prasmol@rediffmail.com</email>
</Journal-Info>
<article>
<article-id pub-id-type='other'>10.22376/ijpbs.2019.10.1.p1-12</article-id>
<issue_number>Volume 5 Issue 3</issue_number>
<issue_period>2014 (July- September)</issue_period>
<title>EVALUATION OF ANTIOXIDANT POTENTIALS OF LEAF AQUEOUS AND METHANOLIC EXTRACTS OF CALOPHYLLUM INOPHYLLUM IN RELATION TO TOTAL PHENOL AND FLAVONOID CONTENTS </title>
<abstract>The leaves, barks, flowers, fruits and seeds of  lessThan i greaterThan Calophyllum inophyllum lessThan /i greaterThan  are widely used in traditional practices. Here in the present study, we aimed to evaluate  lessThan i greaterThan in vitro lessThan /i greaterThan  antioxidant potential of leaf aqueous and methanolic extracts of  lessThan i greaterThan C. inophyllum  lessThan /i greaterThan in relation to total phenol and flavonoid contents. DPPH (1,1-diphenyl-2-picrylhydrazyl) free radical scavenging and ferric (Fe lessThan sup greaterThan +3 lessThan /sup greaterThan ) reducing power was analyzed for antioxidant activity. The total phenol content was estimated using Folin-Ciocalteu reagent and flavonoid content was estimated spectrophotometrically (AlCl lessThan sub greaterThan 3 lessThan /sub greaterThan ) and calculated as tannic acid and quercetin equivalent respectively. DPPH free radical scavenging and Ferric (Fe lessThan sup greaterThan +3 lessThan /sup greaterThan ) reducing the power of the leaf aqueous and methanolic extracts were increased with the increasing extract concentrations. lessThan b greaterThan   lessThan /b greaterThan Leaf lessThan b greaterThan   lessThan /b greaterThan methanolic extract of  lessThan i greaterThan C. inophyllum lessThan /i greaterThan  (LMECI) showed more free radical scavenging activity and reducing power than the leaf aqueous extract of  lessThan i greaterThan C. inophyllum lessThan /i greaterThan  (LAECI) lessThan i greaterThan .  lessThan /i greaterThan Total phenol contents of aqueous and methanolic extracts were 97± 9.2 and 140.28± 17.1 mg/g respectively. Flavonoid contents of the aqueous and methanolic extracts were 88.94±2.94 and 177.06±5.29 mg/g respectively. The present study exhibited that the leaf methanolic extract of  lessThan i greaterThan C. inophyllum lessThan /i greaterThan  have more free radical scavenging and reducing power than that of the aqueous extract. It may be due to the presence of relatively more total phenol and flavonoid contents in the leaf methanolic extract. </abstract>
<authors>SUMANA DUTTA AND SANJIB RAY</authors>
<keywords>poly phenols, flavonoids, Calophyllum inophyllum, antioxidant, reducing power.</keywords>
<pages>441-450</pages>
</article>
</Journal>
