10.22376/ijpbs.2019.10.1.p1-12 Volume 5 Issue 3 2014 (July- September) Antimicrobial activity of alcoholic and aqueous extracts from lessThan i greaterThan Syzygium aromaticum lessThan /i greaterThan (clove) was evaluated against six Gram-negative bacteria, three Gram-positive bacteria and one fungus isolate. Clove extracts demonstrated broad spectrum antimicrobial activities against the tested microorganisms. Gram-positive bacteria were more sensitive than Gram-negative bacteria (MICs and MBCs of 62.5 to 250 μg/ml and 62.5 to 500 μg/ml) respectively. Interestingly, lessThan i greaterThan Psuedomonas aeruginosa lessThan /i greaterThan 359 ETT which is resistant to most antibiotics was relatively more sensitive than other Gram-negative bacteria. While nhexane extracts showed very low activity against the test microorganisms, methanol extract was recorded as the most active extract against lessThan i greaterThan Pseudomonas aeruginosa lessThan /i greaterThan ATCC 27853, lessThan i greaterThan E. coli lessThan /i greaterThan ATCC25922, lessThan i greaterThan Staphylococcus aureus lessThan /i greaterThan 375 at MBC of 62.5 μg/ml. Clove buds essential oils were characterized by GC/MS. Benzyl Alcohol (56.2362 %) and Eugenol (32.5%) were recorded as the major components in clove oil followed by β- Caryophyllene (8.97%) and Ocimene (1.126%). Therefore, the study shed the light on the efficacy of plant extracts to combat pathogens which will help as natural antimicrobial agents of sustainable eco-friendly botanical bactericides. HAYAM S. ABDELKADER AND EMAN M. HALAWANI Syzygium aromaticum , antibacterial activity, GC/MS, MIC, MBC. 389-401