10.22376/ijpbs.2019.10.1.p1-12 Volume 5 Issue 3 2014 (July- September) lessThan i greaterThan Homalium zeylanicum lessThan /i greaterThan is a rare and phytochemically less explored tropical tree. Chemical examination of bark and leaf of this species yielded phenolic compounds 3-Phenyl coumarin (1) and 4'-O-Methyl-Epigallo catechin (2). The structures of the compounds were established on the basis of various NMR spectral data. The extracts of bark, leaf and their isolated compounds showed both antioxidant and anticancer activities in lessThan i greaterThan in vitro lessThan /i greaterThan mode. The acetate derivative of compound 2 showed significant anticancer activity against human cancer cell line IMR-32 (IC lessThan sub greaterThan 50 lessThan /sub greaterThan 6.26 µg/ml) in the MTT assay. RACHALA VINOD KUMAR, KATAKAM BABITHA, LAKUMA DEVI, A NIRANJAN KUMAR, KVNS SRINIVAS, J KOTESH KUMAR, SHAILENDRA PRATAP SINGH AND PARAMJIT GROVER Homalium zeylanicum, Antioxidant activity, Anticancer activity, Phenolic compounds. 176-182