10.22376/ijpbs.2019.10.1.p1-12 Volume 5 Issue 2 2014 (April - June) Disinfectants were tested for their inhibitory activities against commonly occurring bacterial strains Acinetobacter baumannii, Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumonia, Staphylococcus aureus and fungal strains like Candida albicans and Aspergillus niger. The inhibition was recorded by measuring the zone of inhibition of the disinfectants on the tested organisms. The results revealed that the disinfectants Sepsonil DX Cream, Sarvodin, Povidone Iodine 7.5% Solution USP, Sterital, Sidol + (Cetrimide and Chlorohexidine Gluconate), Sidol, Sterilhandz, Sepsonil DX, Microcleer + Chlorhexidine Surgical Wash and Povidone-Iodine Cleaning Solution U.S.P. 10% w/v Surgical Scrub were very effective as it inhibited the growth of Acinetobacter baumannii (BAA-1605), Methicillin resistant Staphylococcus aureus (ATCC 43300), Escherichia coli (ATCC 25922, ATCC 8739, BAA196, BAA198, BAA199, BAA 200, BAA 201 and BAA 457), Pseudomonas aeruginosa (BAA-2109), Klebsiella pneumonia (ATCC 51503), Staphylococcus aureus (ATCC 6538) and Pseudomonas aeruginosa (ATCC 9027). Only disinfectants Microcleer + Chlorhexidine Surgical Wash and Povidone-Iodine Cleaning Solution U.S.P. 10% w/v Surgical Scrub were resulted antifungal activity against Candida albicans (ATCC 10231) and Aspergillus niger (ATCC 16404).  GEETHA G. N, REKHA S , K. R. RAGHUNATHA REDDY , DR. S. N. VINAYA BABU ,DR. D. M. RAVI CHAND AND P. V. RAO Carbapenem resistant K. pneumonia (CRKP), Methicillin resistant Staphyloccous aureus (MRSA), resistance, antimicrobial, novel disinfectant. 785-790