10.22376/ijpbs.2019.10.1.p1-12 Volume 5 Issue 2 2014 (April - June) Among the various hereditary diseases known, there are a few rare diseases which differ from the others in manifestations. One such example is the Sickle cell trait which is usually asymptomatic. Here, we discuss about a symptomatic case which will lead to a difficulty in diagnosis. lessThan br / greaterThan SHANTHI.B. AND VASANTHAN.M. HbS, Electrophoresis, IVP 427-429