10.22376/ijpbs.2019.10.1.p1-12 Volume 5 Issue 1 2014 (January - March) Effect of ethanol, methanol and petroleum ether extracts from the leaves of lessThan i greaterThan Cardiospermum canescens lessThan /i greaterThan Wall. was studied against human pathogenic bacterial strains of lessThan i greaterThan Escherichia coli lessThan /i greaterThan lessThan i greaterThan , lessThan /i greaterThan lessThan i greaterThan Salmonella typhi lessThan /i greaterThan lessThan i greaterThan and lessThan /i greaterThan lessThan i greaterThan Klebsiella pneumonia lessThan /i greaterThan lessThan i greaterThan and the antibiotic sensitivity of bacterial strains was also analyzed by using Bauer–Kirby method. Finally leaf powder was subjected to lessThan /i greaterThan physicochemical and preliminary phytochemical evaluations to establish the quality and purity of the drug. In the Physicochemical studies, loss on drying, total ash value, acid insoluble ash, water insoluble ash, various extractive values etc., were carried out. Further, qualitative tests for various functional groups like triterpenoids, alkaloids, glycosides etc., were carried out. HPTLC profile was also established with ethyl acetate, and methanolic extracts. lessThan i greaterThan The results obtained from the study concluded that leaf powder of this plant is a great potential source as an antibacterial agent and preliminary phytochemical studies revealed the presence of lessThan /i greaterThan triterpenoids, alkaloids, tannins, flavonoids and proteins. G.PENCHALA PRATAP,G.SUDARSANAM AND MOHD. KASHIF HUSSAIN Medicinal Plants, Antibacterial activity, Ethanolic and Methanolic and Petroleum Ether Extracts 1088-1095