10.22376/ijpbs.2019.10.1.p1-12 Volume 5 Issue 1 2014 (January - March) Rooted in invigorating pharmacological applications of carbazole, herein a successful synthesis of some novel and highly potent carbazole derivatives by economically viable means using casual laboratory agents and robust synthetic strategies is detailed. A short linear sequence has been followed to furnish the desired effectual molecules (2-8) having promising anti-microbial activities. All new analogues have been characterized by UV-Vis, FTIR, lessThan sup greaterThan 1 lessThan /sup greaterThan H and lessThan sup greaterThan 13 lessThan /sup greaterThan C NMR, MS and elemental analysis data. The novel chemical moieties have been tested for their bactericidal activity against Methicillin-resistant lessThan i greaterThan Staphylococcus aureus, Escherichia coli lessThan /i greaterThan and for fungicidal property against lessThan i greaterThan Aspergillus flavus lessThan /i greaterThan using agar well diffusion assay showing remarkable antimicrobial potential. ZUBI SADIQ , ERUM AKBAR AND NARJIS NAZ Carbazole derivatives, Synthesis, Antibacterial activity, Fungicidal property 455-464