10.22376/ijpbs.2019.10.1.p1-12 Volume 5 Issue 1 2014 (January - March) A rapid and efficient synthesis of 4,6-Dimethylpyrimidine-2(1H )-one has been carried out from acetylacetone and urea in dry media in the presence of an environmentally friendly non-corrosive, non-toxic and recyclable catalyst in 85% yield under microwave irradiation conditions. DEEPIKA AND SHARWAN K DEWAN Pyrimidine-2-one, Dry media, MW, Urea, Acetyl acetone 352-354