10.22376/ijpbs.2019.10.1.p1-12 Volume 4 Issue 4 2013 (October - December) The combined effect of salicylic acid (SA) (100, 200 and 400 ppm) and water stress (waterlogging and drought) on growth, reactive oxygen species generation and activities of enzymatic and non-enzymatic antioxidants were studied in soybean ( lessThan i greaterThan Glycine max lessThan /i greaterThan L. Merr.) leaves.The results proved that the interaction of salicylic acid with water stress significantly increased total protein content and decreased reactive oxygen species (superoxide anion radical and hydrogen peroxide) in soybean leaves. Water stress also motivated enzymatic (superoxide dismutase (SOD), catalase (CAT), ascorbate peroxidase (APX) and glutathione reductase (GR)) and non-enzymatic (carotenoids, ascorbic acid, nonprotein thiol and proline) activity, while they had a declining trend as a consequence of increasing SA level. It showed prominent role of SA and a sign of oxidative damage in experimental models. . Further investigation to evaluate long term water stress effects is recommended. MEENAKSHI MISHRA UMESH KUMARAND VEERU PRAKASH Catalase, Glycine max, Reactive oxygen species, Salicylic acid, Superoxide dismutase, Water stress, 81-97