10.22376/ijpbs.2019.10.1.p1-12 Volume 4 Issue 4 2013 (October - December) There is a lack of information regarding the alterations in liver metabolities induced by Imidacloprid Insecticide. In the present study, the fresh water teleost lessThan i greaterThan Channa punctatus lessThan /i greaterThan (Bloch) were exposed to Imidacloprid Insecticide for 96h to assess the Biochemical constituents of Glycogen, Proteins, Lipids and Cholesterol of liver tissue. The liver tissue showed significant depletion of Glycogen, Protein and Lipids and significant increase of Cholesterol. In view of results, the present study reports metabolic dysfunction in response to Imidacloprid toxicity in the test fish. B.PADMA PRIYA AND Y.AVASN MARUTHI Channa punctatus, Imidacloprid, Biochemical and Liver. 50-54