10.22376/ijpbs.2019.10.1.p1-12 Volume 4 Issue 4 2013 (October - December) The present investigation was an attempt to evaluate the possible ameliorative effect of lessThan i greaterThan Eclipta alba lessThan /i greaterThan on carbon tetrachloride (CCl lessThan sub greaterThan 4 lessThan /sub greaterThan ) – induced lipid peroxidation in liver of mice lessThan i greaterThan in vitro lessThan /i greaterThan . Antioxidant activity of medicinally important plant lessThan i greaterThan Eclipta alba lessThan /i greaterThan was determined by DPPH – radical scavenging activity. Liver tissue was collected from healthy Swiss albino female mice weighing 30-35 gm. Liver homogenates were prepared and used for various treatments (CCl lessThan sub greaterThan 4 lessThan /sub greaterThan with and without hydro-alcoholic extract of lessThan i greaterThan Eclipta alba lessThan /i greaterThan ) followed by analysis of lipid peroxidation and protein content. The results revealed that addition of CCl lessThan sub greaterThan 4 lessThan /sub greaterThan (5-50 µg/ml) to liver homogenate caused a significant increase in lipid peroxidation which was maximum at 10 µg/ml. An addition of hydro-alcoholic extract of lessThan i greaterThan Eclipta alba lessThan /i greaterThan (25-150 µg/ml) significantly reduced CCl lessThan sub greaterThan 4 lessThan /sub greaterThan (10 µg/ml) - induced lipid peroxidation in concentration-dependent manner. The result was compared with standard drug Liv. 52. The study confirmed the ameliorative effect of the hydro-alcoholic extract of lessThan i greaterThan Eclipta alba lessThan /i greaterThan even higher than the Liv. 52, which may be attributed due to its antioxidative property as revealed by DPPH radical scavenging activity measured. MONALI PATEL AND R. J. VERMA Carbon tetrachloride, Eclipta alba, Lipid peroxidation, Liver, Mice 877-884