10.22376/ijpbs.2019.10.1.p1-12 Volume 4 Issue 4 2013 (October - December) lessThan i greaterThan Grewia nervosa lessThan /i greaterThan (Lour) Panighrahi, belonging to the family Malvaceae s.l. is widely distributed along the Western Ghats of India. Although it has been commonly used in traditional medicine, the medicinal properties have not been scientifically evaluated. Phytochemical analysis established the presence of phenolic compounds, tannins, alkaloids and saponins in leaves. The aqueous and methanol extracts from leaves and bark of lessThan i greaterThan G. nervosa lessThan /i greaterThan were investigated for medicinal properties using lessThan i greaterThan in vitro lessThan /i greaterThan assays. The methanol extract of leaves demonstrated 97.5% inhibition of α-amylase activity. Additionally, the methanol extract of leaves also demonstrated antioxidant activity (5.41± 0.23 mmol/g, dw) that was higher compared to aqueous extract (3.32±0.45 mmol/g, dw). Further the methanol extract of bark exhibited anti-lipoxygenase activity indicative of its potential to control inflammatory activity. These results suggest that lessThan i greaterThan Grewia nervosa lessThan /i greaterThan would be a potential source for treatment of diabetes and its associated complications such as oxidative stress and inflammation S.N. MEENA,S C GHADI AND M.K. JANARTHANAM Grewia nervosa, α-amylase inhibition, anti-lipoxygenase, antioxidant activity 821-828