SYNTHESIS OF SOME NOVEL TETRAZOLE SUBSTITUTED BENZIMIDAZOLES AND THEIR EVALUATION AS ANTIOXIDANTS

10.22376/ijpbs.2019.10.1.p1-12

Volume 4 Issue 4 2013 (October - December) SYNTHESIS OF SOME NOVEL TETRAZOLE SUBSTITUTED BENZIMIDAZOLES AND THEIR EVALUATION AS ANTIOXIDANTS A series of tetrazole derivatives (3a-h) were synthesized and screened for antioxidant activity by nitric oxide free radical scavenging activity. All the synthesized compounds were structurally elucidated by spectral techniques such as IR, lessThan sup greaterThan 1 lessThan /sup greaterThan H NMR spectroscopy and mass spectrometry. The compounds 3b, 3d 3f and 3h exhibited promising antioxidant activities which were found to be comparable with standard ascorbic acid. M.A.KALE AND M.R.PEHARKAR Nitric oxide scavenging assay, Tetrazole, Benzimidazole, Antioxidant. 675-681