10.22376/ijpbs.2019.10.1.p1-12 Volume 4 Issue 4 2013 (October - December) Citrus plants are the rich source of secondary metabolites which includes alkaloids, steroids, tanins, flavonoids, phenols and polyphenols. Having the rich source of polyphenols and natural flavonoids draw attention to screen the phytochemical compounds and their beneficial activities from different solvents. The present investigation explore the lessThan i greaterThan in vitro lessThan /i greaterThan antioxidant activity of orange ( lessThan i greaterThan Citrus sinensis lessThan /i greaterThan ) peel extract from different solvents gives reliable information and best extraction procedures to screen the phytochemicals. Among the different solvent extracts methonolic extract exhibits the highest lessThan i greaterThan in vitro lessThan /i greaterThan scavenging activity followed by other solvent extracts which includes Ethanolic, Hexane, Benzene, Ethyl acetate, and chloroform with IC lessThan sub greaterThan 50 lessThan /sub greaterThan values 65.44,120, 138.45, 151.34, 170.34, 185.35 with 55.6 % inhibitory concentration of ascorbic acid. The screening and scavenging activities of secondary metabolites form different solvents may improve the best extraction procedures and functional activities of beneficial compounds. In this regard to reach a conclusion that methonolic orange peel extract followed by ethonolic extract showed their high potential effectiveness as antioxidant activity when compared to the other solvent extracts. S. SWAPNA REKHA AND M. BHASKAR Citrus sinensis (L) orange peel, phytochemicals, in vitro antioxidants,solvents. 405-412