10.22376/ijpbs.2019.10.1.p1-12 Volume 4 Issue 2 2013 (April - June) Gram negative anaerobes are associated with periodontal inflammation leading to destruction of the periodontal ligament, supportive bone and subsequent tooth loss. This study was designed to characterize lessThan i greaterThan Prevotella and Porphromonas lessThan /i greaterThan species from patients with odontogenic infections and evaluate their susceptibility pattern to amoxicillin a drug empirically administered in Nigerian dental clinics. Isolates were presumptively identified as lessThan i greaterThan Prevotella and lessThan /i greaterThan lessThan i greaterThan Porphyromonas lessThan /i greaterThan species by conventional cultural and biochemical analysis. Antimicrobial susceptibility pattern of the isolates to amoxicillin was determined by agar dilution method. lessThan i greaterThan Prevotella lessThan /i greaterThan and lessThan i greaterThan Porphyromonas lessThan /i greaterThan species showed susceptibility of 80% and 94% to amoxicillin respectively. lessThan i greaterThan Prevotella lessThan /i greaterThan and lessThan i greaterThan Porphyromonas sp. lessThan /i greaterThan resistant to amoxicillin are involved in oral infections in our population. Correct identification of these species and their corresponding susceptibility pattern will be of public health importance in selecting antibiotics for therapy in order to achieve better treatment outcomes. CHUKWU EMELDA E M. SC, NWAOKORIE FRANCISCA O. PH. D., UMEIZUDIKE KEHINDE A. FMCDS, KOLAWOLE MOSUMOLA M. SC., AGU REUBEN C. B. SC, ADESIDA SOLAYIDE A. PH. D. AND COKER AKITOYE O. PH. D. Anaerobes, antimicrobial susceptibility pattern, Prevotella species, Porphyromonas species. 760-765