10.22376/ijpbs.2019.10.1.p1-12 Volume 4 Issue 2 2013 (April - June) Plants have richest source of bioactive compounds as phytochemicals in the form of secondary metabolites. In this study three lessThan i greaterThan Cestrum lessThan /i greaterThan species lessThan i greaterThan C. aurantiacum, C. nocturnum and C. diurnum lessThan /i greaterThan were investigated for phytochemicals and revealed presence of Alkaloids, Anthraquinones, Cardiac Glycosides, Carbohydrates, Flavonoids, Phenolic compound, Tannins and Terpenoids. Antioxidant potential was estimated by DPPH and FRAP assay and lessThan i greaterThan C. diurnum lessThan /i greaterThan showed higher antioxidant potential than that of the other two species in both assays lessThan i greaterThan . lessThan /i greaterThan Different solvents such as ethanol, methanol, butanol, propanol and acetone were used to extract the bioactive compounds from the leaves of these plant species. The antimicrobial activity of these solvent extracts was tested against three bacterial ( lessThan i greaterThan S. typhi lessThan /i greaterThan , lessThan i greaterThan P. aeruginosa lessThan /i greaterThan and lessThan i greaterThan K. pneumoniae lessThan /i greaterThan ) and two fungal species ( lessThan i greaterThan Aspergillus lessThan /i greaterThan and lessThan i greaterThan Trichoderma lessThan /i greaterThan ) by agar well diffusion method. lessThan i greaterThan C. aurantiacum lessThan /i greaterThan showed maximum antibacterial activity, and maximum antifungal activity was detected for butanol extract of lessThan i greaterThan C. nocturnum lessThan /i greaterThan against lessThan i greaterThan Aspergillus lessThan /i greaterThan . PRASAD M.P.,APOORVA PRABHU,MONICA SINGH THAKUR,AND YOGESH M. RUPAREL Cestrum, Phytochemical, Antioxidant, Antimicrobial 673-678