<?xml version="1.0" encoding="utf-8"?>
<Journal>
<Journal-Info>
<name>International Journal of Pharma and Bio Sciences</name>
<website>ijpbs.net</website>
<email>editorijpbs@rediffmail.com (or) editorofijpbs@yahoo.com (or) prasmol@rediffmail.com</email>
</Journal-Info>
<article>
<article-id pub-id-type='other'>10.22376/ijpbs.2019.10.1.p1-12</article-id>
<issue_number>Volume 4 Issue 2</issue_number>
<issue_period>2013 (April - June)</issue_period>
<title>IDENTIFICATION OF CagA HARBORING HELICOBACTER PYLORI FROM BUCCAL SWAB COLLECTED FROM TOBACCO ADDICTED WOMEN SUBJECTS </title>
<abstract>  lessThan i greaterThan Helicobacter pylori lessThan /i greaterThan  is recognized as the major etiological agent of chronic gastritis, gastric adenocarcinoma and lymphoma. The present study was carried out to investigate the presence of  lessThan i greaterThan Helicobacter pylori lessThan /i greaterThan  in buccal salivary sample collected from tobacco addicted women from India and to study certain virulence properties including detection of the presence of cancer producing gene  lessThan i greaterThan cagA lessThan /i greaterThan . Here, sixteen bacterial isolates were identified as  lessThan i greaterThan Helicobacter pylori lessThan /i greaterThan  and they were different in their colony morphology i.e., rugose (37.5%), opaque (62.5%). All of them were motile, protease positive, highly biofilm forming. All of them were found resistant to chloramphenicol, tetracycline but sensitive to ampicillin and kanamycin. But, resistance was found to amoxicillin, trimethoprim and streptomycin for 50%, 25% and 12.5% isolates, respectively. PCR analysis revealed five isolates to possess  lessThan i greaterThan cagA lessThan /i greaterThan  gene. Results of the present study predicted that these  lessThan i greaterThan Helicobacter pylori  lessThan /i greaterThan isolates may be a potential threat for developing gastric infection in future.</abstract>
<authors>SMRITIKANA BISWAS, DIBYENDU BHOWMICK AND CHANDRADIPA GHOSH</authors>
<keywords>Saliva, Helicobacter pylori, antibiotic susceptibility, biofilm, cagA.</keywords>
<pages>165-175</pages>
</article>
</Journal>
