10.22376/ijpbs.2019.10.1.p1-12 Volume 4 Issue 2 2013 (April - June) D-Pinitol, the major constituent of soybean plant is known as an insulin mimicker. There is a growing interest in the use of D-Pinitol as a food supplement because of its reported efficacy in lowering blood glucose levels with no side effects and nil toxicity. Pinitol was first isolated from pine tree and later from many plants of the lessThan i greaterThan Leguminosae lessThan /i greaterThan family. D-Pinitol has been recently reported from lessThan i greaterThan Pisonia alba lessThan /i greaterThan (synonym- lessThan i greaterThan Pisonia grandis lessThan /i greaterThan ) of the lessThan i greaterThan Nyctaginaceae lessThan /i greaterThan family (Patent Pending 385/CHE/2010). As the demand for pinitol as a food supplement and as a pharmaceutical increased, any attempt to isolate it from natural sources including plants is considered highly worthy. This review covers literature reported on isolation of D-Pinitol from plants during the period 1940 to May 2011. G. POONGOTHAI AND SHUBASHINI K. SRIPATHI D-Pinitol, Insulinomimetic, Food supplement, Isolation, Plant sources. 992-1009