10.22376/ijpbs.2019.10.1.p1-12 Volume 4 Issue 2 2013 (April - June) Nosemosis is one of the most widespread disease of honey bees with potentially serious effects on beekeeping. The transmission of nosema disease to the adult honey bees infecting epithelial cells, lining the midgut after spores are ingested causes various clinical symptoms ,including digestive disorders ,shortened life span ,decreased population size and negative effects on honey production capacity. In this review, the historical and recent data on Nosema ,covering the tissue tropism, pathology ,diagnoses, multiplication, phylogeny and genetics, virulence, clinical symptoms, control, and transmission of this important honey bee parasite and discuss these within the wider theoretical concepts, have been summarized. MUDASAR MANZOOR, V. MATHIVANAN, GH. NABI SHAH,G M MIR AND SELVISABHANAYAKAM Nosema cerana, Nosema apis, , phylogeny, pathology, virulence, control 923-937