10.22376/ijpbs.2019.10.1.p1-12 Volume 4 Issue 2 2013 (April - June) The causative agents of skin infection are bacteria, fungi and in specific dermatophytes. Many infectious diseases have been treated with plant extracts. The free and bound flavonoids fractions of lessThan i greaterThan Wrightia tinctoria (Roxb) lessThan /i greaterThan R.Br. (Apocynaceae), leaves were tested against 10 bacterial, 3 fungal and 4 dermatophytic strains affecting the skin using disc diffusion and broth micro dilution method. The free flavonoidal extract showed maximum activity against lessThan i greaterThan Bacillus subtilis lessThan /i greaterThan (gram positive), lessThan i greaterThan Proteus vulgaris lessThan /i greaterThan (gram negative), lessThan i greaterThan Candida albicans lessThan /i greaterThan (fungus) and lessThan i greaterThan Trichophyton rubrum lessThan /i greaterThan (dermatophyte). The bound flavonoidal extract showed maximum activity against lessThan i greaterThan Staphylococcus aureus lessThan /i greaterThan (gram positive), lessThan i greaterThan Escherichia coli lessThan /i greaterThan (gram negative), lessThan i greaterThan Candida albicans lessThan /i greaterThan (fungus) and lessThan i greaterThan Epidermophyton floccosum lessThan /i greaterThan (dermatophytes) among the various tested organisms. The bounded flavonoidal extract (activity index 0.58) had strong activity against dermatophytes. This provides a lead that, flavonoidal extract could be used for direct incorporation into formulations for effective treatment and a scientific rationale for the traditional use of lessThan i greaterThan Wrightia tinctoria lessThan /i greaterThan in treating skin infections. T. SENTHIL KUMAR, D. VENKAPPAYYA,VILAMBI N.R.K. REDDY AND R. MANAVALAN. Antibacterial AntifungalAntidermatophytic Flavonoidal extractsWrightia tinctoria (Roxb.) R. Br. 889-897