10.22376/ijpbs.2019.10.1.p1-12 Volume 4 Issue 2 2013 (April - June) Herbal infusions of nine traditionally used medicinal plants were screened for total phenolic content (TPC), radical scavenging activity (RSA) and oxidative DNA damage protecting capacity by chemical assays. The TPC was determined in order to know its correlation with RSA. The extracts of lessThan i greaterThan T. cordifolia lessThan /i greaterThan and lessThan i greaterThan C. spectabilis lessThan /i greaterThan presented highest TPC values (34.21 ± 0.93 and 28.36 ± 1.05 mg GAE/g) and showed strong RSA (96.29 ± 0.91 and 84.68 ± 0.90 mg TE/g). A significant relationship (R lessThan sup greaterThan 2 lessThan /sup greaterThan = 0.915, lessThan i greaterThan p lessThan /i greaterThan lessThan 0.01) was found between TPC and RSA indicating that phenolics are contributing to the antioxidant properties of these plants. The qualitative analysis of DNA damage protecting activity revealed the potential of lessThan i greaterThan T. cordifolia lessThan /i greaterThan , lessThan i greaterThan V. negundo lessThan /i greaterThan , lessThan i greaterThan O. sanctum lessThan /i greaterThan and lessThan i greaterThan C. phlomides lessThan /i greaterThan extracts as potent DNA damage protecting agent. Present study validates the uses of these herbs in various herbal ailments to treat many illnesses associated with oxidative stress. RACHNA GARG, DEVIHALLI CHIKKAIAH MOHANA AND KIRAGANDUR MANJUNATH Antioxidant activity,Total phenolic content, Radical scavenging activity,Oxidative DNA damage, Correlation analysis. 657-664