10.22376/ijpbs.2019.10.1.p1-12 Volume 4 Issue 2 2013 (April - June) The importance of antioxidant constituents in maintenance of health attracted research in plant based antioxidants. Presence of amino acid argenine and secondary metabolites like flavonoids and phenolic compounds and antibacterial activity leads for the evaluation of antioxidant activity of lessThan i greaterThan Sebastiania chamaelea lessThan /i greaterThan leaf aqueous extracts. lessThan i greaterThan In-vitro lessThan /i greaterThan free radical scavenging LC lessThan sub greaterThan 50 lessThan /sub greaterThan at 100-90 µg/ml, and r educing ability EC lessThan sub greaterThan 50 lessThan /sub greaterThan at 175µg/ml are closely resembled to that of the standard drug ascorbic acid. The antioxidant activity also supported by the evaluation of the total phenolic compounds 235 µg/ml Gallic acid equivalent and flavonoids 210µg/ml as Quercetin Equivalent. lessThan i greaterThan S. chamaelea lessThan /i greaterThan antioxidant activity may also support the herbal usage against vertigo, astringent, remedy for syphilis and diarrhoea. N. YASODAMMA, K.S. SHANTHI SREE, C. ALEKHYAAND A.JOB ROGER BINNY Freeradical,IC50,EC50,Reducingpower,Phenoliccompounds,Sebastianiachamaelea, Flavonoids. 623-629