10.22376/ijpbs.2019.10.1.p1-12 Volume 4 Issue 2 2013 (April - June) lessThan i greaterThan Vitex trifolia lessThan /i greaterThan belongs to the family lessThan i greaterThan lamiaceae. lessThan /i greaterThan The anti-inflammatory property of the aqueous extract of the leaves of lessThan i greaterThan Vitex trifolia lessThan /i greaterThan L. was studied by carrageenan induced paw oedema, granuloma pouch and formaldehyde induced arthritis method. in albino rats. The extract lessThan i greaterThan was lessThan /i greaterThan administered at the varying doses of 500, 1000 & 2000 mg/kg body weight per orally to three groups of six animals each. Increasing the doses of the test drug produced signicant (p lessThan 0.001) increased in percentage of inhibition of paw oedema and significant inhibition of exudate formation. The extract shows significant anti-inflammatory activity when compared with the control and comparable efficacy with the standard. The present study suggests that the aqueous extract of the leaves of lessThan i greaterThan vitex trifolia lessThan /i greaterThan L. has anti-inflammatory property. A. PFUZIA, R.K. BHARATI DEVI , KH. SHARATCHANDRA,B. N. DEBASHREE, BANYLLA SN AND KH. SANIA MONICA Anti-inflammatory, carrageenan, granuloma pouch, formaldehyde arthritis 588-593