CHEMICAL INFORMATION FROM GC-MS STUDIES OF METHANOLIC LEAF EXTRACT OF ANDROGRAPHIS PANICULATA AND DATURA METEL AND THEIR ANTIBACTERIAL ACTIVITY AGAINST ISOLATED PSEUDOMONAS AERUGINOSA (PB112) STRAIN

10.22376/ijpbs.2019.10.1.p1-12

Volume 4 Issue 1 2013 (January - March) CHEMICAL INFORMATION FROM GC-MS STUDIES OF METHANOLIC LEAF EXTRACT OF ANDROGRAPHIS PANICULATA AND DATURA METEL AND THEIR ANTIBACTERIAL ACTIVITY AGAINST ISOLATED PSEUDOMONAS AERUGINOSA (PB112) STRAIN The present study was carried out to determine the phytochemical profile and antibacterial activity of lessThan i greaterThan Andrographis paniculata lessThan /i greaterThan and lessThan i greaterThan Datura metel lessThan /i greaterThan extracts. For the present investigation, extracts of lessThan i greaterThan A. paniculata lessThan /i greaterThan and lessThan i greaterThan D.metel lessThan /i greaterThan were prepared by extraction in methanol, chloroform, acetone and benzene and were compared for their antibacterial activity. The antibacterial activities were assessed by measuring the diameter of the inhibition zones by Disc diffusion method. In comparison to this different extracts, the methanol extract showed better antibacterial activity against the isolated lessThan i greaterThan P.aeruginosa lessThan /i greaterThan bacterial strain tested. The chemical composition of methanol extracts of these two plants were investigated by GC-MS, while the mass spectra of the compounds found in the extract was matched with the NIST and WILEY library. SOMERITA PANDA AND P.K.BANDYOPADHYAY Andrographis paniculata, Datura metel, P.aeruginosa, antibacterial activity, GC-MS analysis. 909-915