10.22376/ijpbs.2019.10.1.p1-12 Volume 4 Issue 1 2013 (January - March) Candida is a yeast like fungus causing commonest fungal infections. Being endogenous in nature, in individuals with risk factors can lead to candidiasis. Candidiasis caused by various species,important being C.albicans. As there are chronic,treatment failure cases noted in these infections it is important to study the antifungal susceptibility pattern of candida. Objectives: Study of prevalence, speciation and antifungal susceptibility of Candida species from samples received by Microbiology Laboratory was the aim. Methods: 150 isolates were considered for the study. Candida was identified from clinical samples by wetmount, gram stain and culture on SDA. The organisms were further speciated by germ tube test, cornmeal agar morphology, sugar assimilation and fermentation tests. Antifungal sensitivity was performed by using disc diffusion method. Results: The most common isolate found to be Candida albicans (61.3%) followed by non albicans Candida mainly C.tropicalis (18%), C.glabrata 16(10.6%),C.guillermondii 10(6.6%) and C.krusei 5 (3.3%). 90% of isolates were from mucocutaneous area. The common predisposing factors observed were pregnancy, HIV infection, diabetes, prolonged contact with water. Resistance to commonly used antifungal agents found to be Fluconazole – 17.3%, Ketoconazole­­- 11.3%, Nystatin -5.3%, and Amphotericin-B - 2%.Conclusion: C.albicans is the common cause of candidiasis followed by C.tropicalis, C.glabrata, C.krusei. Antifungal susceptibility testing need to be carried out before starting therapy because of varying susceptibility pattern in different species of the Candida. SUNILKUMAR BIRADAR, AMRUTHKISHAN U, GANGANE R, SHEEBA P, AMAR N, PRAVEEN D AND SREEKANTHA Candida; candidiasis;C.albicans;Antifungal susceptibility. 1113-1118