10.22376/ijpbs.2019.10.1.p1-12 Volume 1 Issue 1 2010 (January - March) Commercial detergents are available in plenty , and the toxic effects to humans is studied experimentally on an animal and compared for its effects on humans.The study is aimed for the possible toxic effects resulting from the misuse of Lyarkina solution used as a detergent .The inflammatory effect is caused by Lyarkina which is a solution of Sodium hypochlorite with or without sodium hydroxide solution lessThan i greaterThan Objective : lessThan /i greaterThan The possible toxic effects resulting from the misuse of Lyarkina solution used as a substitute for detergents .  lessThan i greaterThan Experimental set-up : lessThan /i greaterThan Derna Hospital ,Omar El-Mukthar university ., Derna. lessThan i greaterThan Methods : lessThan /i greaterThan The inflammatory effects of Lyarkina on experimental animals (Rabbits) and on humans is studied .The number of patients on whom the experiment is performed crossed over 100 , and 50% were females .  lessThan i greaterThan Results : lessThan /i greaterThan The study revealed that in most patients the inflammation of the skin was evident by severe itching caused by severe irritation and in some patients the eczematic reactions were observed. Even psychological effects were also observed ,where some vegetables ,citrus fruits , garlic and onions influenced the toxicity.  lessThan i greaterThan Conclusion: lessThan /i greaterThan The study confirmed the toxic effects to humans on misuse of the Lyarkine solution and should be avoided and replaced by the regular detergents. Dr. Hassen A. H. Bennasir,Shanmugam Sridhar Detergents ,Lyarkina , Eczematic reaction ,Skin inflammation , Prevention, Sodium Hypochlorite -