10.22376/ijpbs.2019.10.1.p1-12 Volume 4 Issue 1 2013 (January - March) lessThan i greaterThan Abrus precatorius lessThan /i greaterThan is known to possess antiseptic and anti-inflammatory activity, which makes it useful in treatment of wounds. In the present study, different concentrations of ethanolic extracts of lessThan i greaterThan A. precatorius lessThan /i greaterThan stem were investigated for evaluation of wound healing activity in rats. Wistar albino rats have been grouped into three sets- first set was uninfected with wounds, second set was infected with lessThan i greaterThan Staphylococcus Aureus lessThan /i greaterThan and third set was infected with lessThan i greaterThan Candida albicans lessThan /i greaterThan . Different concentrations of ethanolic extracts of lessThan i greaterThan A.precatorius lessThan /i greaterThan (60, 90, 120mg\\g) were applied topically in the form of ointment to wounds inflicted on rats and healing was assessed by the rate of wound contraction and epithelialization period. On 15 lessThan sup greaterThan th lessThan /sup greaterThan day, the extract treated rats exhibited 71 % reduction in uninfected wound area as compared to control which exhibited 59 % contraction. In case of wound infected with S.aureus, the extract treated rats exhibited 72 % reduction in wound area as compared to control which exhibited 51 % contraction approximately. In antimicrobial testing, ethanolic extracts of lessThan i greaterThan A.precatorius lessThan /i greaterThan were screened against clinical wound isolates of lessThan i greaterThan Staphylococcus aureus lessThan /i greaterThan , lessThan i greaterThan Pseudomonas aeruginosa lessThan /i greaterThan and lessThan i greaterThan Candida albicans lessThan /i greaterThan . All extracts were found to be active against the pathogens, while the ethanolic extract exhibited highest inhibition and document the beneficial effects for acceleration of wound healing activity in rats. Phytochemical tests showed the presence of tannins, triterpenes, glycosides, alkaloids, antraquinones and carbohydrates in crude extracts of lessThan i greaterThan A.precatorius. lessThan /i greaterThan ABHILASHA SHOURIE AND KUNTAL KALRA Abrus precatorius , anti-microbial, epithelization, ,infected wound , healing 91-101