10.22376/ijpbs.2019.10.1.p1-12 Volume 3 Issue 3 2012 (July - September) lessThan i greaterThan Acne vulgaris lessThan /i greaterThan (Acne) is the most common skin disorder characterized by non-inflammatory comedones or inflammatory papules, pustules and nodules. Although acne does not pose serious threat to general health, it is one of the most socially distressing conditions especially for adolescents. The acne inflammation is triggered by pus forming bacteria recognized as lessThan i greaterThan Propionibacterium acnes lessThan /i greaterThan and lessThan i greaterThan Staphylococcus epidermidis lessThan /i greaterThan . Acne therapy includes prolonged use of comedolytic agents, antibiotics and anti-inflammatory agents that are known to cause many side effects. Moreover, the widespread and long-term use of antibiotics over the years has unfortunately led to emergence of resistant strains. To avoid side effects, traditional or herbal formulations are preferred. Herbs are safe, efficacious and multifunctional. Medicinal plant extracts are known to have enormous therapeutic potential. Plant-based preparations with little or no side effects are cyclically returning to complement dermatological therapy. They serve as safer choice or in some cases is the only effective treatment. Amrita, G. Greeshma, N. Deepa M. And Poornima, E.H. Acne vulgaris, Comedones, Propionibacterium acnes and Staphylococcus epidermidis. 987-997