International Journal of Pharma and Bio Sciences
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10.22376/ijpbs.2019.10.1.p1-12
Volume 1 Issue 4
2010 (October - December)
Antimicrobial Activity Of Constituents Identified In Essential Oils From Mentha And Cinnamomum Through GC-MS
GS/MS of essential oils from Cinnamomum camphorum and Mentha piperita revealed the main chemical components, bornyl acetate, terpinen-4-ol, 1,8 cineole, camphor, eugenol, limonene, ά-pinene, β pinene, geraniol, cinnamaldehyde, linalool, borneol and menthol.GC-MS studies of the essential oils of Mentha piperita and Cinnamomum camphorum have revealed the major constituents as menthol and camphor respectively as per the retention time (area 30.07% ,mol.wt. 156.26 for menthol and 67.66% area, mol.wt.142 for camphor). Two terpenoids were subjected for the study of their antimicrobial activity against E.coli and S.aureus. Menthol showed greater zone of inhibition in 24 hrs. at maximum 2% concentration , while less zone of inhibition in 24 hrs. was observed at 2% concentration with camphor.Structure – activity relationship has been observed in the following trend. Methoxy terpene greaterThan Alcoholic Terpene greaterThan Ketonic terpene On the basis of the above observation these terpenes can be used as natural medicines in the treatment of several diseases like cold & Flu, infectious diseases, bronchitis and also as flavouring liquors, cosmetics, fragrances etc.
Neerja Gupta,Goldy Saxena
Essential oils, Menthol, Camphor, Antimicrobial activity
715-720