International Journal of Pharma and Bio Sciences
ijpbs.net
editorijpbs@rediffmail.com (or) editorofijpbs@yahoo.com (or) prasmol@rediffmail.com
10.22376/ijpbs.2019.10.1.p1-12
Volume 3 Issue 2
2012 (April - June)
High Sensitive C-Reactive Protein And Apolipoprotein B Levels In Polycystic Ovary Syndrome
Polycystic ovary syndrome [PCOS] is associated with abdominal obesity, insulin resistance and dyslipidemia. Women with PCOS may be at an increased risk for the development of type 2 diabetes mellitus. Atherosclerosis is characterised by an inflammatory response of the arterial wall due to endothelial injury. Hence low grade chronic inflammation may independently predict coronary heart disease [CHD]. Serum high sensitive C-reactive protein [hsCRP], a marker of chronic subclinical inflammation which is actively involved in atherogenesis is considered a predictor of future CVD. We investigated hsCRP and apolipoprotein B [apoB] levels in a small population of 30 women with PCOS and 30 control subjects. In women with PCOS the levels of hs-CRP, apolipoprotein B and waist-to-hip ratio were significantly elevated when compared with controls. Screening with hsCRP and apolipoprotein B may provide a better risk assessment in patients with PCOS.
V.M.Vinodhini, V.Devisri, W.Ebenezer William, M.Muthulakshmi, Anjalakshi Chandrasekar And S. Gnanasambandam
Apolipoprotein B, atherosclerosis, cardiovascular risk, diabetes, hsCRP, inflammation, PCOS
719-724