10.22376/ijpbs.2019.10.1.p1-12 Volume 3 Issue 2 2012 (April - June) To investigate the immunomodulatory activity of flavonoid fractions of lessThan i greaterThan Terminalia catappa lessThan /i greaterThan in Swiss albino mice. The flavonoid fraction of lessThan i greaterThan T.catappa lessThan /i greaterThan was administrated intraperitonealy at a dose of ED lessThan sub greaterThan 50 lessThan /sub greaterThan to healthy albino mice. Assessment of immunomodulatory activity was carried out by assessment of neutrophil adhesion and phagocytic index. Intraperitonealy administered Tcff showed a significant increase in neutrophil adhesion and phagocytic index.This study demonstrates that the Tcff shows immunomodulatory effect. M.Saroja, R.Santhi And S.Annapoorani Phagocytic index, neutrophil adhesion, T.catappa, flavonoid fraction 418-422