10.22376/ijpbs.2019.10.1.p1-12 Volume 3 Issue 2 2012 (April - June) The penguin wing oyster lessThan i greaterThan Pteria penguin lessThan /i greaterThan whole body extract was obtained with different solvents. The whole body extracts were assayed for antibacterial activity using agar well diffusion technique against human pathogens. The extracts derived from acetone and chloroform exhibited broad antibacterial activity. Highest activity was exhibited against lessThan i greaterThan Klebsiella pneumoniae lessThan /i greaterThan (6 mm) and lessThan i greaterThan Staphylococcus epidermidis lessThan /i greaterThan (5.5 mm) by the crude extract of acetone and against lessThan i greaterThan Salmonella paratyphi lessThan /i greaterThan B (5.5 mm) by the chloroform extract. The column-purified acetone fractions showed higher activity against lessThan i greaterThan Klebsiella pneumoniae lessThan /i greaterThan (6 mm), lessThan i greaterThan Streptococcus pneumoniae lessThan /i greaterThan (4.5 mm). The MIC of the 100% acetone fraction was found to be equally lower for the pathogens lessThan i greaterThan Klebsiella pneumoniae lessThan /i greaterThan (250µg) and lessThan i greaterThan Staphylococcus epidermidis lessThan /i greaterThan (250µg). Therefore 100% acetonated fraction of the extract of lessThan i greaterThan P. penguin lessThan /i greaterThan can be concluded as potent antimicrobial compound against these human pathogens. T. Mohanraj, K. Prabhu And S. Lakshmanasenthil Marine bioactive products, Antibacterial activity, Pteria penguin, Human pathogens 65-70