10.22376/ijpbs.2019.10.1.p1-12 Volume 3 Issue 2 2012 (April - June) Transition metal (II) complexes of the type ML lessThan sub greaterThan 1 lessThan /sub greaterThan [where M=Cd(II) and Hg(II), L lessThan sub greaterThan 1 lessThan /sub greaterThan =Schiff base derived from 2-amino, 4-methyl phenol and O-hydroxy acetophenone] have been prepared, characterized by elemental analysis, molar conductivity, IR, electronic spectra, NMR spectral and X-ray diffraction studies. Molar conductivity measurements indicate that the complexes are non-electrolyte in nature. The analytical data confirm metal to ligand ratio in the complexes were 1:1. IR spectral data suggests that the ligand (AMPOHA) behaves as tridentate ONO donar system. X-ray diffraction studies determine monoclinic crystal system for these complexes. The Schiff base and their metal complexes have been tested for their antibacterial and antifungal activity using disc diffusion methods. Suraj B. Ade, M.N. Deshpande And D.G. Kolhatkar Schiff base, Metal chelates, Spectral studies and Anti-microbial activity. 174-181