10.22376/ijpbs.2019.10.1.p1-12 Volume 3 Issue 2 2012 (April - June) Leaves of lessThan i greaterThan Momordica charantia lessThan /i greaterThan L or bitter melon or bitter gourd (Cucurbitaceae) an active ingredient of many ayurvedic preparations mainly against diabetes was studied for its pharmacognisical characters. The trace elements and the mineral content of the leaves were also evaluated. Ethanolic extracts of the leaves reported lessThan i greaterThan in vitro lessThan /i greaterThan antibacterial activities against gram negative bacteria such as lessThan i greaterThan Salmonella typhi, Pseudomonas fluorescens, Pseudomonas aeruginosa and Escherichia coli. lessThan /i greaterThan The pathogens were tested by disc diffusion assay method and a minimum inhibitory concentration was evaluated. An attempt was made to compare the activity of the extract with a standard antibiotic ciprofloxin. The pharmacognisical and the phytochemical constituents help in proving the authencity of the drug. In addition it proves the efficacy of the plant as an antibacterial agent. Poonam Sethi bitter gourd, Momordica, antibacterial, trace element, minerals 01-05