10.22376/ijpbs.2019.10.1.p1-12 Volume 3 Issue 1 2012 (January - March) lessThan i greaterThan Murraya koenigii (Linn) Spreng lessThan /i greaterThan (Indian curry leaf) is a highly valued culinary plant with the aqueous extract of its leaves which are reported to exhibit diverse biological activities. Considering free radical mechanism in hepatotoxicity, dietary antioxidants could provide protection in conditions including alcoholic liver disease. The objective of this study was to investigate its effects on biochemical markers of liver function affected in diseased state. Two high doses of 1 g/kg and 2 g/kg were evaluated for its hepatoprotection on ethanol-induced liver toxicity in Wistar rats. The aqueous extract showed potent antioxidant activity, and at both doses produced a significant increase in reduced glutathione levels with comparable reduction in serum glutamate pyruvate transaminase and alkaline phosphatase levels. Only 1 g/kg dose depleted malondialdehyde levels in comparison to ethanol. Histopathology of liver samples confirmed the above findings. The results suggested significant benefits of nutritive antioxidant compounds in lessThan i greaterThan M. koenigii lessThan /i greaterThan contribute to its potential hepatoprotective activity Sadhana Sathaye, Poornima D Amin, Vinam B Mehta, Vijay B Zala, Ramesh DKulkarni, Harpreet Kaur And Roopali G Redkar Curry leaves, hepatoprotection, antioxidants, liver functional enzymes 430-438