10.22376/ijpbs.2019.10.1.p1-12 Volume 3 Issue 1 2012 (January - March) The present paper discusses studies related to synthetic organic compounds against a Bacterial plant pathogen ( lessThan i greaterThan Xanthomonas campestris pv. campestris - lessThan /i greaterThan ITCC) lessThan i greaterThan lessThan b greaterThan s lessThan /b greaterThan lessThan /i greaterThan train isolated from cabbage leaves, a causative of black rot disease on crucifers. In order to achieve the goal of the present studies, solutions of total seven Pyrazolones and Pyridines and three Schiff bases in Di-Methyl formamide (DMF) were evaluated in- lessThan i greaterThan vitro lessThan /i greaterThan against this pathogen using disc diffusion method on nutrient agar and nutrient broth media. These compounds were established on the basis of conventional methods viz. m. pt., elemental analysis and with the help of advanced spectroscopic techniques viz. I.R., NMR and Mass spectral analysis. The pyridine based compounds were found superior to other compounds being studied. Two compounds viz., 3-methyl-1-Phenyl-5-pyrazolone ( lessThan b greaterThan C5 lessThan /b greaterThan ) and 2-Benzyl Pyridine ( lessThan b greaterThan C10 lessThan /b greaterThan ) recorded significant anti-microbial activity against lessThan i greaterThan Xanthomonas campestris pv. campestris in-vitro lessThan /i greaterThan with minimum inhibitory concentration (MIC) of 5 mg/10 mL of the solvent. The observed lab activities of the compounds under study against the pathogen were subjected to Structure Activity Relationship (SAR) studies correlating structural parameters viz. Heat of formation (HF), Zero point energy (ZPE) Dipole moment (DM), Hydration energy (HE), Refractivity (RF), Polarizability (PZ), Surface area (approx) (SAA), Surface area (Grid), (SAG) and Volume (VOL) of the compounds obtained from computational HYPERCHEM Professional software. The observed SAR equations which are significant statistically are also reported. The whole lessThan b greaterThan lessThan i greaterThan in-vitro lessThan /i greaterThan lessThan /b greaterThan antibacterial study was focused to find out the solution for pest management of phytopathogen - lessThan i greaterThan Xanthomonas campestris pv. campestris lessThan /i greaterThan on local area crops of crucifers including Mustard. Vinod Kumar Sewariyaa, Richa Shrivastava B, GBKS Prasad B And Kishor Arorac Xanthomonas campestris pv. campestris, Black rot, Pyrazolones, Pyridines and Schiff base. 441-453