International Journal of Pharma and Bio Sciences
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10.22376/ijpbs.2019.10.1.p1-12
Volume 3 Issue 1
2012 (January - March)
Effect Of Advanced Gestation On Cellular Activity In Respiratory System In Females: A Study Of Alveolar Ventilation Parameters In Pregnant Women Of North India
This study was conducted on 100 pregnant women in third trimester of uncomplicated pregnancy (cases) and 100 non pregnant women (control). Cases were further subdivided as per the gestational age into two groups of ≤ 34 weeks and greaterThan 34 weeks gestation. Pulmonary function test (PFT) parameters FVC, FEV lessThan sub greaterThan 1 lessThan /sub greaterThan , PEFR and FEF lessThan sub greaterThan (25-75%) lessThan /sub greaterThan , FEV lessThan sub greaterThan 1 lessThan /sub greaterThan /FVC lessThan sub greaterThan . lessThan /sub greaterThan were evaluated with digital Medspiror. The aim of the study was to assess and compare the change in PFT parameters in third trimester of pregnancy vis a vis those in the non pregnant control subjects of the same age. The study revealed a decrease in PFT values in the ≤ 34 weeks group as compared to the control group which was statistically not significant. But a comparison of PFT in greaterThan 34 vs control group, showed significant decrease in all PFT,s except FEV lessThan sub greaterThan 1 lessThan /sub greaterThan / FVC ratio. A similar decline was seen while comparing the subgroups of the study group i.e. ≤34 wks Vs greaterThan 34wks groups. This study validates the physiological changes in pulmonary functions during third trimester of pregnancy which if accentuated are likely to affect the outcome of the pregnancy.
Neeraj, John Pramod And Joydeep Singh
Pulmonary Function Tests, Pregnancy, Early third trimester, Late third trimester,
31-37