10.22376/ijpbs.2019.10.1.p1-12 Volume 2 Issue 4 2011 (October - December) New 3-substituted [3, 4-dihydropyrimidinones]-Indolin-2-ones have been synthesized and tested for Anti-inflammatory activity by caragenen induced rat paw method. Among them compounds AJ lessThan sub greaterThan 16 lessThan /sub greaterThan , AJ lessThan sub greaterThan 15 lessThan /sub greaterThan , AJ lessThan sub greaterThan 14 lessThan /sub greaterThan , AJ lessThan sub greaterThan 13 lessThan /sub greaterThan and AJ lessThan sub greaterThan 12 lessThan /sub greaterThan exhibited higher anti inflammatory activity. However, these anti-inflammatory activities are lower than standard Diclofenac Sodium. M. Ajitha And K. Rajnarayana Dihydropyrimidinones, Indole-2-ones, Anti-inflammatory activity 81-90