10.22376/ijpbs.2019.10.1.p1-12 Volume 2 Issue 4 2011 (October - December) The ethanolic extract of PC an SS were screened for its anti inflammatory activity against 5- HT and Histamine induced inflammation model. 200mg/kg dose of this extract were given orally to study its effect on the exudative and proliferate phases of the inflammatory reaction using the plethysmograph. The results were compared with the standard drug 5mg/kg of Diclofenac sodium. Plant extract at tested concentration produced significant anti-inflammatory activity K.Chandrasekaran And L.Suseela PC , SS, Histramine, 5-HT, Plethysmograph 77-80