Int J Pharm Bio Sci Volume 16 Issue 1, January - March, Pages:1-12
A Review on an Epilepsy Epidemiology Focuses on its Measures, Data Sources, and Global Burden of Disease from 2010-2019 Before the Onset of the COVID- 19 Pandemic
This review includes all the additional evidence and cutting-edge knowledge regarding the epidemiology of epilepsy that the previous article skipped. There are fewer articles related to the epidemiology of the disease and some on the burden of disease. To bring about educational change in line with the vision for the existing health system, we at the institutional level gather in this article a full description of the epidemiology of epilepsy, aggregating all standard measure concepts and different sources with some evidence of observational studies according to the World Health Organization. To make comparisons on the topic, we limited our investigation to the last ten years, from 2010 to 2019, which fell before the COVID-19 pandemic. We aimed to update a review and analyse the burden of the disease at the global level. We studied and concluded that, globally, in 2019, distinctive epilepsy incidents increased in all ages by [1.5 million (1.1–2.0)] in males and [1.3 million (0.9–1.7)] in females; prevalent cases increased by [13.0 million (9.9–16.2)] in male and [12.0 million (9.1–15.1)] in female as compared to 2010, respectively; death 114010.9 (95% UI, 100177.7 to 129928.1); high SDI (socio-demographic index) regions showed the lowest death as compared to low SDI regions in all age and sex. We updated estimates for up to 2023 and explored new data, methodological improvements, and up-to-date available information to help allocate resources.
Keywords: Epilepsy, Epidemiology, Data sources, Measures, Global, Prevalence
Full HTML:
Kaculini CM, Tate-Looney AJ, Seifi A. The history of epilepsy: from ancient mystery to modern misconception. Cureus. 2021; 13(3): e13953.
Fisher RS, Acevedo C, Arzimanoglou A, Bogacz A, Cross J-H, Elger C-E, et al. ILAE official report: a practical definition of epilepsy. Epilepsia. 2014; 55(4): 475-82.
The World Health Organization (2024) Epilepsy. WHO, Geneva.
Scheffer IE, Berkovic S, Capovilla G, Connolly M-B, French J, Guilhoto L, et al. ILAE classification of the epilepsies: position paper of the ILAE Commission for Classification and Terminology. Epilepsia. 2017; 58(4): 512-21.
Falco-Walter JJ, Scheffer IE, Fisher RS. The new definition and classification of seizures and epilepsy. Epilepsy Res. 2018; 139: 73-9.
Trinka Eugen, Cock H, Hesdorffer D, Rossetti A-O, Scheffer I-E, Shinnar S, et al. A definition and classification of status epilepticus-report of the ILAE task force on classification of status epilepticus. Epilepsia. 2015; 56(10): 1515-1523.
Thurman D. ILAE: Annual reports by the commission on epidemiology USA, 2014.
Kumari L, Mazumder PM. Efficacy of Murraya koenigii leaf extract for attenuating the progression of diabetic nephropathy in animal models. Int J Pharm and Bio Sciences. 2013; 4(3): 678-93.
Beghi E, Giussani G, Nichols E, Allah F-A, Abdela J, Abdelalim A, et al. GBD 2016 Epilepsy collaborators. Lancet Neurol. 2019; 18(4): 357-75.
Manorenj S. National epilepsy day: importance and history, Pace hospital India, 2023 [Cited 2023 Nov 17]. Available from: https://www.pacehospital.com/national-epilepsy-day.
Daugherty J, Waltzman D, Sarmiento K, Xu L. Traumatic brain injury related deaths by race/ethnicity, sex, intent and mechanism of injury - United States, 2000-2017. MMWR Morbidity and Mortality Weekly Report. 2019; 68(46):1050-56.
Stubbs J, Thornton A, Sevick J, Silverberg ND, Barr AM, Honer WG, et al. Traumatic brain injury in homeless and marginally housed individuals: A systematic review and meta-analysis. L Pub Health. 2020; 5(1):e19-e32.
Sveinsson O, Andersson T, Mattsson P, Carlsson S, Tomson T. Clinical risk factors in SUDEP: A nationwide population based case control study. Neurology. 2020; 94(4): e419-29.
Pathak SJ, Yousaf MIK, Shah VB. Sudden Unexpected Death in Epilepsy. Stat-pearls Intern [Cited 2022 Dec 19]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK559104/.
Chahal CAA, Salloum MN, Alahdab F, Gottwald JA, Tester DJ, Anwer LA, et al. Systematic review of the genetics of sudden unexpected death in epilepsy: potential overlap with sudden cardiac death and arrhythmia-related genes. J Am Heart Assoc. 2020; 9(1): e012264.
Chen Z, Brodie MJ, Ding D, Kwan P. Editorial: Epidemiology of epilepsy and seizures. Front Epid. 2023; 3: 1273163.
Mula M. The comorbidities of epilepsy explained. Expert Rev Neurother. 2020; 20(12): 1207-19.
WHO and World Federation of Neurology: ATLAS Country resources for neurological disorders. WHO [Cited 2017 Sep 15]. Available from: https://www.who.int/publications/i/item/atlas-country-resources-for-neurological-disorders.
WHO Global Health Workforce Statistics: WHO Global Health Observatory, Geneva. 2024. Available from:https://www.who.int/data/gho/data/themes/topics/health-workforce.
IHME. Global burden of disease. Health Metrics and Evaluation at the University of Washington. 2023. Available from: https://www.healthdata.org/research-analysis/gbd.
Beghi E, Giussani G, Nichols E, Abd-Allah F, Abdela J, Abdelalim J. Epilepsy Collaborators. Global, regional, and national burden of epilepsy, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet Neurol. 2019; 18 (4): 357-75.
Thijs RD, Surges R, Obrien TJ, Sander JW. Epilepsy in adults. The Lancet. 2019; 393(10172): 689-701.
Bennett SD, Cross JH, Chowdhury K, Ford T, Heyman I, Coughtrey AE, et al. Clinical effectiveness of the psychological therapy Mental Health Intervention for Children with Epilepsy in addition to usual care compared with assessment-enhanced usual care alone: a multicentre, randomised controlled clinical trial in the UK. The Lancet. 2024; 403: 1254-66.
Asadi-Pooya AA, Brigo F, Lattanzi S, Blumcke I. Adult epilepsy. The Lancet. 2023; 402(10399): 412-24.
Hullett PW, Lowenstein DH. Major advances in epilepsy research in 2023. The Lancet. 2024; 23(1):19-20.
Scgmitz B, Lattanzi S, Vonck K, Kalviainen R, Nashef L, Ben ME. Cenobamate in refractory epilepsy: Overview of treatment options and practical considerations. Epilepsia Open. 2023; 8(4):1241-55.
Weatherall M. Epilepsy stigma: a long story. The Lancet. 2023; 22(12):1107-1115.
Kishore L, Mehta A. Assessing guidelines for diabetes management in hypertension. Int J Pharmacogn Pharm Res. 2024; 6(2): 32-36.
Beghi E. The epidemiology of epilepsy. Neuro-epidemiology. 2020; 54(2): 185-91.
Giroux M-M , Sardinha L, Stockl H, Meyer S-R , Godin A , Alexander M, et al. A framework to model global, regional, and national estimates of intimate partner violence. BMC Med Res Meth. 2022; 22: 159.
Zhang Y-J, Kong X-M, Lv J-J, Yang C-H, Li X-Y, Wang L, et al. Analysis of the global burden of disease study highlights the global, regional, and national trends of idiopathic epilepsy epidemiology from 1990 to 2019. Prev Med Rep. 2023; 36(12): 102522.
Hu Y, Shan Y, Du Q, Ding Y, Shen C, Wang S, et al. Gender and socioeconomic disparities in global burden of epilepsy: An analysis of time trends from 1990-2017. Fontiers Nero. 2021; 12: 643450.