International Journal of Pharma and Bio Sciences
    ISSN 0975-6299

Int J Pharm Bio Sci Volume 14 Issue 2, April-June, Pages:11-17

Histopathological Study of Skin Lesions in A Tertiary Care Hospital: A Cross - Sectional Study/A Retrospective Study

Dr Kirti Nishant Vyas,Dr Jyoti Prakash Sapre and Dr Nilam Hardik Patel

The skin has many functions and is a complex organ. Epidermis with skin adnexa, melanocytic system, dermis and subcutis are the three main anatomic components of the skin. Skin is the body's largest sensory organ of the body and acts asis a barrier against various harmful environmental agents. The clinical features of skin lesions are related to the underlying pathological processes. Skin conditions fall into three clinical groups (1) well-defined appearance and distribution, (2) with a characteristic pattern but with a variety of underlying clinical conditions, (3) with a variable presentation and no constant association with underlying conditions. Although dermatology is a clinical subject, an understanding of cellular changes in skin disease can give helpful insights into the pathological processes. This study was carried out to find outdetermine the frequency of various skin lesions at dermatology OPD which are also confirmed by histopathological studies. Thus histopathological diagnosis will help clinicians in managingmanage patients in terms of further requiring clinical investigations and treatment. This Furthermore, this study gives ideas about various skin lesions in correlation with age, sex and site of involvement at tertiary care hospitals and it. It will help to educate the community and physicianphysicians accordingly after the study results. A 3-year retrospective study of 120 cases was done in a tertiary care hospital, Nadiad, from 1st August 2019 to 31st August 2022. The diagnosis of these skin lesions was confirmed by histopathological examination with routine hematoxylin and eosin stain. A total of 120 cases were studied, 61 cases (50.8%) were males, and 59 cases (49.1%) were females. In males’ commonest Males' most common lesions were granulomatous lesions, leprosy (7.5%) followed by %), and keloid lesions. In females, the commonestmost standard lesions were keloids (10.0%) and, granulomatous lesions, leprosy (5.83%). Skin biopsy is one type of integrated approach whichthat helps in increasingincrease the accuracy of diagnosis and better management of the patients.

Keywords: Non -neoplastic skin lesions, Granulomatous lesions, Histopathological study
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  1. Abubakar SD, Tangaza AM, Sahabi SM, Legbo JN. Histopathological pattern of skin lesions in Usmanu Danfodiyo university teaching hospital Sokoto, Nigeria. Afr J Cell Pathol. 2016;6(10):5.
  2. Nagar K, Shah N, Bhalodia J. Histopathologic pattern of skin diseases in tertiary health care centre: A retrospective study of 133 cases. Int Arch Integr Med. 2021;8(11):78.
  3. Adhikari RC, Shah M, Jha AK. Histopathological Spectrum of skin diseases in a tertiary skin health and referral centre. J Pathol Nep. 2019 April 3;9(1):1434-40. doi: 10.3126/jpn.v9i1.23172.
  4. Singh A. Nirmal AK, Gupta P, Jha JK. Histopathological review of dermatological procedures with a keynote to granulomatous lesions: A Retrospective Study. Ind J Pub Health Res Dev. 2018;9(6):18.
  5. World Health Organization. Epidemiology and management of common skin disease in children in developing countries. Geneva: World Health Organization; 2005.
  6. Italiya S, Purohit A, Gohel A, Prajapati H. Histopathological study of Non Neoplastic skin lesions. Asian J Pharm Clin Res July. 2022;15(9):180-4.
  7. Goyal N, Jain P, Malik R, Koshti ASpectrum of Non-Neoplastic Skin Disease-A Histopathology Based Clinicopathological Correlation Study.Sch J App Med Sci.2015;3(1F)444-449.
  8. Kumar V, Sharan A, Poriya S, Kundu S. Clinico-Histopathological correlation of Nonneoplastic Dermatological lesions. Int J Res Rev. 2022;10(1):24-30.
  9. Chalise S, Dhakhwa R, Pradhan SB. Histopathological Study of Skin Lesions in a Tertiary Care Hospital: a Descriptive Cross-sectional Study. JNMA J Nepal Med Assoc. 2020 April 30;58(224):218-22. doi: 10.31729/jnma.4799, PMID 32417857.
  10. Gupta I, Kaira V, Gupta K. Bothale KA, Mahore SD. Clinical profile of nonneoplastic skin lesions: A prospective cross-sectional study. Indian J Clin Exp Dermatol. 2019;8:53-7.
  11. Moorthy BN, Kumar P, Chatura KR, Chandrasekhar HR, Basavaraja PK. Histopathological correlation of skin biopsies in leprosy.IJDVL2001. Indian J Dermatol Venereol Leprol. 2001;67(6):299-301. PMID 17664782.
  12. Younas M, Haque A. Spectrum of Histopathological Features in non-infectious Erythematous and papulosquamous Diseases. Int J Pathol. 2004;2:24-30.
  13. Patel NG, Patel NJ. Epidemiological study of skin(dermatological) diseases and their treatment in North Gujarat. Asian J Pharm Clin Res. 2010;3:40-2.
  14. D' Costa G, Bharambe BM. The spectrum of non-infectious erythematous, papular and squamous lesions of the skin. Indian J Dermatol. 2010;55(3):225-8. doi: 10.4103/0019-5154.70666. PMID 21063511.
  15. Goswami P, Parekh M, Goswami A. Histopathology spectrum of skin lesions in teaching institution. J Family Med Prim Care. 2022;11(8):4610-13. doi: 10.4103/jfmpc.jfmpc_2016_21, PMID 36353033.
  16. George VP, Sowmya S SS, Krishnan S KS. A histopathological study of skin biopsy specimens in a tertiary care hospital with a keynote on clinicopathological correlation. Annals Pathol Lab Med. 2020;7(1):A39-45. doi: 10.21276/apalm.2670.
  17. Bezbaruah R, Baruah M. Histopathological spectrum of skin lesions-A hospital-based study. Indian J Appl Res. 2018;8:51-2.
  18. Achalkar GV. Clinicopathological evaluation of non-neoplastic and neoplastic skin lesions: a study of 100 cases. Indian J Pathol Oncol. 2019;6(1):118-22. doi: 10.18231/2394-6792.2019.0021.
  19. Gaikwad SL, Kumawat UD, Sakhare NA. D'costa GF. Histopathological Spectrum of skin lesions-Experience at a rural based hospital. International J of current research. 2016;8:36223-27.
  20. Mamatha K, Susmitha S, Vijayalaxmi SP, Sathyashree KV. Disha BS. Histopathological Spectrum of dermatological lesions-An experience at the tertiary care centre. IP archives of cytology and histopathology research. 2018;3(2):83-8.
  21. Singh S, Debnath A, Vhakravarty DD. S, Chaubey RN. Histopathological evaluation of skin lesions with particular reference to skin adnexal tumours in a tertiary centre of North Eastern India –A three-year study. IOSR JDMS.IOSR-IDMS.2016;15(2):34-39.
  22. Kafle SU, Chaudhary D, Yamu S, Jha K. Diagnose significance of clinicopathological concordance in various Spectrum of skin disorders, BJHS. 2020;5(1)11:955-59.
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