International Journal of Pharma and Bio Sciences
 
 
    ISSN 0975-6299
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ORIGINAL RESEARCH ARTICLE
Int J Pharm Bio Sci Volume 2 Issue 3, 2011 (July - September), Pages:223-230

Study Of Variations In Serum Lipid Profile And Transaminase Levels In Overt Hypothyroidism

 

Dr. D.V.Krishnaveni
DOI:
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Abstract:

This study was undertaken to evaluate the variations in thyroid profile, lipid profile and transaminase levels in overt hypothyroid patients, compared to healthy controls. Thirty hypothyroid patients, both male & female, in the age group of 20 to 50 years (study group) and 30 age & sex matched healthy subjects (control group) were enrolled in the study. We found significant increase in mean levels of total cholesterol, serum triglycerides, LDL-c, AST & TSH and significant decrease in T3 & T4 in study group compared to controls. There was no significant difference in HDL –c values between two groups. The ALT and VLDL-c values were near the upper limits of normal range in study group, while they were near the lower limit in control group, the difference being significant.

Keywords: Hypothyroidism, Thyroid Profile, lipid profile, Transaminases
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