Int J Pharm Bio Sci Volume 7 Issue 2, 2016 (April - June), Pages:11-17
IN-VITRO SCREENING OF SOME MEDICINAL PLANTS ON BREAST, OVARY AND COLON CANCER CELL LINES.
ALLABAKASHA M. SHAIKH, DR. B. SHRIVASTAVA, DR. K. G. APTE, DR. P B. PARAB, DR. PANKAJ SHARMA, SAMPAT D. NAVALE. AND S. V. PAYGUDE
DOI:
Abstract:
In the present study, the aqueous extracts of Curcum caesia, Curcuma longa, Curcuma zedoaria and Gloriosa superba was studied for their in vitro cytotoxic activity against human breast cancer (MCF-7), colon cancer (HCT-116) and ovarian cancer (PA-1) cell lines using sulphorhodamine B (SRB) assay. The results showed that aqueous extract of Curcuma zedoaria and Gloriosa superba exhibited the prominent inhibitory effect whereas Curcuma longa and Curcuma caesia have moderate to weak effects in in vitro conditions as compared with standard drug 5-fluorouracil.
Keywords: Human cancer cell lines; Invitro Cytotoxicity test; SRB assay; Indian medicinal plants.
