International Journal of Pharma and Bio Sciences
ijpbs.net
editorijpbs@rediffmail.com (or) editorofijpbs@yahoo.com (or) prasmol@rediffmail.com
10.22376/ijpbs.2019.10.1.p1-12
Volume 2 Issue 3
2011 (July - September)
Synthesis And Cytotoxicity Evaluation Of Diarylpyrazine And Dihydropyrazine Derivatives
Some 2,3-diaryl pyrazines and 5,6-diaryl-2,3-dihydropyrazine were synthesized and evaluated for their cytotoxicity study. 2,3-Diarylpyrazines were prepared from oxidation of 5,6-diarly-2,3-dihydropyrazine by sulfur. The synthesized compounds were tested for their cytotoxicity effects toward (MT-29) cancer cell line using MTT-assay. The results showed compounds 4a and 4b were two most active compounds.
Parisa Miralinaghi, Mona Salimi, Sara Shirmohammadli And Mohsen Amini
Diarylpyrazine, Diaryldihydropyrazine, Cytotoxicity, MT-29,
60-64