International Journal of Pharma and Bio Sciences
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10.22376/ijpbs.2019.10.1.p1-12
Volume 8 Issue 3
2017 (July - September)
In-vitro antioxidant activity of pet ether, methanolicandEthyl acetate extract of helicteres isora linn.
The work is aimed to evaluate the antioxidant properties of three extracts (Pet Ether, Ethyl Acetate, and Methanolic) of lessThan i greaterThan Helicteres isora lessThan /i greaterThan . In the present work antioxidant activity was determined by 1, 1-diphenyl-2-picrylhydrazyl (DPPH) and Superoxide assay method and their IC lessThan sub greaterThan 50 lessThan /sub greaterThan values were calculated. Results showed that all the extracts of lessThan i greaterThan Helicteres isora lessThan /i greaterThan shows significant free radicals inhibition. The methanolic extract shows maximum activity in both methods. DPPH radicals were inhibited at IC lessThan sub greaterThan 50 lessThan /sub greaterThan =35.61ug/ml with 68.76% antioxidant activity in methanolic extract while Superoxide (SOD) radicals were inhibition at IC lessThan sub greaterThan 50 lessThan /sub greaterThan =61.25 ug/ml with 61.23% antioxidant activity at 100ug/ml.The results suggest that three samples of lessThan i greaterThan Helicteres isora lessThan /i greaterThan possess almost similar antioxidant activity in comparison to standards and might be useful for further study of the lessThan i greaterThan Helicteres isora lessThan /i greaterThan plant products and plant as whole for better drug and will help in prevention of chronic life style diseases which justifies the traditional use of this plant.
SUNNY SHARMA AND SEEMA BHARGAVA
Antioxidant, Methanol, Pet Ether, Ethyl Acetate, Ascorbic Acid.
234-237